Immediate Implant Placement in a Patient With Osteoporosis Undergoing Bisphosphonate Therapy: 1-Year Preliminary Prospective Study.
Identifieur interne : 001088 ( Main/Exploration ); précédent : 001087; suivant : 001089Immediate Implant Placement in a Patient With Osteoporosis Undergoing Bisphosphonate Therapy: 1-Year Preliminary Prospective Study.
Auteurs : Tomas Siebert [Slovaquie] ; Richard Jurkovic [Slovaquie] ; Dagmar Statelova [Slovaquie] ; Juraj Strecha [Slovaquie]Source :
- The Journal of oral implantology [ 0160-6972 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Agents de maintien de la densité osseuse (administration et posologie), Agents de maintien de la densité osseuse (usage thérapeutique), Alvéole dentaire (), Analyse de survie, Diphosphonates (administration et posologie), Diphosphonates (usage thérapeutique), Extraction dentaire, Facteurs de risque, Femelle, Humains, Imidazoles (administration et posologie), Imidazoles (usage thérapeutique), Mandibule (), Mâchoire partiellement édentée (), Mâchoire partiellement édentée (rééducation et réadaptation), Ostéo-intégration (physiologie), Ostéonécrose de la mâchoire associée aux biphosphonates (étiologie), Ostéoporose post-ménopausique (traitement médicamenteux), Perfusions veineuses, Pose d'implant dentaire endo-osseux (), Résorption alvéolaire (), Études de suivi, Études prospectives.
- MESH :
- administration et posologie : Agents de maintien de la densité osseuse, Diphosphonates, Imidazoles.
- physiologie : Ostéo-intégration.
- rééducation et réadaptation : Mâchoire partiellement édentée.
- traitement médicamenteux : Ostéoporose post-ménopausique.
- usage thérapeutique : Agents de maintien de la densité osseuse, Diphosphonates, Imidazoles.
- étiologie : Ostéonécrose de la mâchoire associée aux biphosphonates.
- Adulte d'âge moyen, Alvéole dentaire, Analyse de survie, Extraction dentaire, Facteurs de risque, Femelle, Humains, Mandibule, Mâchoire partiellement édentée, Perfusions veineuses, Pose d'implant dentaire endo-osseux, Résorption alvéolaire, Études de suivi, Études prospectives.
English descriptors
- KwdEn :
- Alveolar Bone Loss (classification), Bisphosphonate-Associated Osteonecrosis of the Jaw (etiology), Bone Density Conservation Agents (administration & dosage), Bone Density Conservation Agents (therapeutic use), Dental Implantation, Endosseous (methods), Diphosphonates (administration & dosage), Diphosphonates (therapeutic use), Female, Follow-Up Studies, Humans, Imidazoles (administration & dosage), Imidazoles (therapeutic use), Infusions, Intravenous, Jaw, Edentulous, Partially (rehabilitation), Jaw, Edentulous, Partially (surgery), Mandible (surgery), Middle Aged, Osseointegration (physiology), Osteoporosis, Postmenopausal (drug therapy), Prospective Studies, Risk Factors, Survival Analysis, Tooth Extraction, Tooth Socket (surgery).
- MESH :
- chemical , administration & dosage : Bone Density Conservation Agents, Diphosphonates, Imidazoles.
- classification : Alveolar Bone Loss.
- drug therapy : Osteoporosis, Postmenopausal.
- etiology : Bisphosphonate-Associated Osteonecrosis of the Jaw.
- methods : Dental Implantation, Endosseous.
- physiology : Osseointegration.
- rehabilitation : Jaw, Edentulous, Partially.
- surgery : Jaw, Edentulous, Partially, Mandible, Tooth Socket.
- chemical , therapeutic use : Bone Density Conservation Agents, Diphosphonates, Imidazoles.
- Female, Follow-Up Studies, Humans, Infusions, Intravenous, Middle Aged, Prospective Studies, Risk Factors, Survival Analysis, Tooth Extraction.
Abstract
The purposes of this preliminary study are to assess the risk of developing bisphosphonate-related osteonecrosis of the jaw (BRONJ) in a patient with osteoporosis using zoledronic acid and to report the results of a 1-year prospective clinical study regarding 5 immediately inserted implants in the anterior mandible. For this comparative prospective study, 24 female patients, aged ≥54 years, were chosen, all with partially edentulous mandibles. Group A consisted of 12 patients with osteoporosis taking zoledronic acid receiving a once-yearly intravenous infusion of zoledronic acid (5 mg). Control group B consisted of 12 other patients without osteoporosis and not taking drugs. In both groups, the remaining teeth were extracted before 120 implants, 3.7-mm wide and 16-mm long, were immediately installed in the interforaminal region of the mandibles. The 1-year implant survival rate was 100%. No apparent necrotic bone was observed among patients receiving zoledronic acid (group A) after implant surgery. Immediate implant osseointegration can be successful in a patient with osteoporosis using bisphosphonates, suggesting the safety of implantology as a treatment modality.
DOI: 10.1563/AAID-JOI-D-13-00063
PubMed: 24041299
Affiliations:
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type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alveolar Bone Loss (classification)</term><term>Bisphosphonate-Associated Osteonecrosis of the Jaw (etiology)</term><term>Bone Density Conservation Agents (administration & dosage)</term><term>Bone Density Conservation Agents (therapeutic use)</term><term>Dental Implantation, Endosseous (methods)</term><term>Diphosphonates (administration & dosage)</term><term>Diphosphonates (therapeutic use)</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Imidazoles (administration & dosage)</term><term>Imidazoles (therapeutic use)</term><term>Infusions, Intravenous</term><term>Jaw, Edentulous, Partially (rehabilitation)</term><term>Jaw, Edentulous, Partially (surgery)</term><term>Mandible (surgery)</term><term>Middle Aged</term><term>Osseointegration (physiology)</term><term>Osteoporosis, Postmenopausal (drug therapy)</term><term>Prospective Studies</term><term>Risk Factors</term><term>Survival Analysis</term><term>Tooth Extraction</term><term>Tooth Socket (surgery)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Agents de maintien de la densité osseuse (administration et posologie)</term><term>Agents de maintien de la densité osseuse (usage thérapeutique)</term><term>Alvéole dentaire ()</term><term>Analyse de survie</term><term>Diphosphonates (administration et posologie)</term><term>Diphosphonates (usage thérapeutique)</term><term>Extraction dentaire</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Imidazoles (administration et posologie)</term><term>Imidazoles (usage thérapeutique)</term><term>Mandibule ()</term><term>Mâchoire partiellement édentée ()</term><term>Mâchoire partiellement édentée (rééducation et réadaptation)</term><term>Ostéo-intégration (physiologie)</term><term>Ostéonécrose de la mâchoire associée aux biphosphonates (étiologie)</term><term>Ostéoporose post-ménopausique (traitement médicamenteux)</term><term>Perfusions veineuses</term><term>Pose d'implant dentaire endo-osseux ()</term><term>Résorption alvéolaire ()</term><term>Études de suivi</term><term>Études prospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Bone Density Conservation Agents</term><term>Diphosphonates</term><term>Imidazoles</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Agents de maintien de la densité osseuse</term><term>Diphosphonates</term><term>Imidazoles</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Alveolar Bone Loss</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Osteoporosis, Postmenopausal</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Bisphosphonate-Associated Osteonecrosis of the Jaw</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Dental Implantation, Endosseous</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Ostéo-intégration</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Osseointegration</term></keywords><keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en"><term>Jaw, Edentulous, Partially</term></keywords><keywords scheme="MESH" qualifier="rééducation et réadaptation" xml:lang="fr"><term>Mâchoire partiellement édentée</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Jaw, Edentulous, Partially</term><term>Mandible</term><term>Tooth Socket</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Bone Density Conservation Agents</term><term>Diphosphonates</term><term>Imidazoles</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Ostéoporose post-ménopausique</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Agents de maintien de la densité osseuse</term><term>Diphosphonates</term><term>Imidazoles</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Ostéonécrose de la mâchoire associée aux biphosphonates</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Infusions, Intravenous</term><term>Middle Aged</term><term>Prospective Studies</term><term>Risk Factors</term><term>Survival Analysis</term><term>Tooth Extraction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Alvéole dentaire</term><term>Analyse de survie</term><term>Extraction dentaire</term><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Mandibule</term><term>Mâchoire partiellement édentée</term><term>Perfusions veineuses</term><term>Pose d'implant dentaire endo-osseux</term><term>Résorption alvéolaire</term><term>Études de suivi</term><term>Études prospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The purposes of this preliminary study are to assess the risk of developing bisphosphonate-related osteonecrosis of the jaw (BRONJ) in a patient with osteoporosis using zoledronic acid and to report the results of a 1-year prospective clinical study regarding 5 immediately inserted implants in the anterior mandible. For this comparative prospective study, 24 female patients, aged ≥54 years, were chosen, all with partially edentulous mandibles. Group A consisted of 12 patients with osteoporosis taking zoledronic acid receiving a once-yearly intravenous infusion of zoledronic acid (5 mg). Control group B consisted of 12 other patients without osteoporosis and not taking drugs. In both groups, the remaining teeth were extracted before 120 implants, 3.7-mm wide and 16-mm long, were immediately installed in the interforaminal region of the mandibles. The 1-year implant survival rate was 100%. No apparent necrotic bone was observed among patients receiving zoledronic acid (group A) after implant surgery. Immediate implant osseointegration can be successful in a patient with osteoporosis using bisphosphonates, suggesting the safety of implantology as a treatment modality.</div></front></TEI><affiliations><list><country><li>Slovaquie</li></country></list><tree><country name="Slovaquie"><noRegion><name sortKey="Siebert, Tomas" sort="Siebert, Tomas" uniqKey="Siebert T" first="Tomas" last="Siebert">Tomas Siebert</name></noRegion><name sortKey="Jurkovic, Richard" sort="Jurkovic, Richard" uniqKey="Jurkovic R" first="Richard" last="Jurkovic">Richard Jurkovic</name><name sortKey="Statelova, Dagmar" sort="Statelova, Dagmar" uniqKey="Statelova D" first="Dagmar" last="Statelova">Dagmar Statelova</name><name sortKey="Strecha, Juraj" sort="Strecha, Juraj" uniqKey="Strecha J" first="Juraj" last="Strecha">Juraj Strecha</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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